Tongue electro-impedance myography: a window into FSHD

Investigators: Benjamin Sanchez PhD, Russell J Butterfield MD PhD

Category: Research - Clinical

Industry and researchers are in need of powerful biomarkers to accelerate efficient drug development and confirmatory drug trials in facioscapulohumeral muscular dystrophy, one of the most common forms of muscular dystrophy resulting in progressive weakness in the face, shoulders, and hip girdle. Sanchez will evaluate the suitability of a novel and convenient multi-sensor depressor designed to measure the ability of the tongue to conduct an externally applied electrical current and store electric charge within as measured with electrical impedance myography (EIM) can serve as a convenient biomarker to assess tongue’s health. The proposed project will produce the basic knowledge required to evaluate our novel technology for monitoring tongue health in patients with FSHD.

Clinical portion approved. Grant extended from 30-Nov-2021 to 30-Jun-2022. Additional funding of $24,250.

Related Material

Progress Update 1

Progress Update 2

See publication A Bioimpedance-Based Device to Assess the Volume Conduction Properties of the Tongue in Neurological Disorders Affecting Bulbar function