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Progress Update: Modulation of DUX4 Production
Apr 17, 2012
Asymmetric Bidirectional Transcription from the FSHD-Causing D4Z4 Array Modulates DUX4 Production
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Massage is promising for muscle recovery
Feb 12, 2012
Researchers at McMaster University have discovered a brief 10-minute massage helps reduce inflammation in muscle.
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Award winning photos of smooth muscle cells may help FSHD research
Feb 1, 2012
Stem cell researcher has become the first Australian to win microscopic image competition.
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Joel Chamberlain RNAi Update
Jan 15, 2012
Recent discoveries provide us with a clearer understanding of how the genetics of FSHD translate into disease.
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Progress Update: DUX4 Activates Germline Genes, Retroelements, and Immune Mediators
Dec 28, 2011
DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy.
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Longitudinal Progression of Edema and Fatty Replacement of Lower Extremity Muscles in FSHD
Nov 28, 2011
Degeneration of muscles in FHSD is associated with fatty replacement on magnetic resonance imaging.
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Modulators of Epigenetic Disease
Nov 27, 2011
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Progress Update: Mechanism of Wnt Signaling in Facioscapulohumeral Muscular
Nov 20, 2011
The gene thought to cause FSHD, Double Homeobox Protein 4 (DUX4), is unusual because it is encoded within each unit (D4Z4) of large arrays present on chromosomes 4 and 10.
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MR Evaluation of Skeletal Muscles
Nov 11, 2011
The main findings describe pervasive inflammation and heterogeneity of affected calf muscles in FSHD.
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Development of anti-DUX4 therapeutics for FSHD
Oct 31, 2011
Test selected compounds for their efficacy in preventing damage caused by DUX4 expression.
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Identifying new therapies and understanding the pathogenesis of FSHD
Oct 19, 2011
An update by Barbara D Page on the work done for the first of a 2-year project titled "Using model organisms to identify new therapies and understand the pathogenesis of FSHD."
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Platform development and candidate drug screening for FSHD: Update
Sep 6, 2011
The Miller Lab has made exciting progress in the development of a platform for screening genes and compounds with activities that affect FSHD-specific pathogenic processes.
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Platform development and candidate drug screening for FSHD
Sep 6, 2011
A major goal of the Seattle FSHD research consortium has been to develop platforms for drug discovery.
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Summary of paper in Molecular Therapy from Joel R. Chamberlain and Davide Gabellini
Aug 9, 2011
Summary of paper in Molecular Therapy from Joel R. Chamberlain and Davide Gabellini
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FSHD Muscle Nuclei Poised for DUX4 Expression
Oct 29, 2010
An international research consortium shows that FSHD muscle nuclei are poised for expression of the toxic DUX4 protein.
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Dr. Rabi Tawil on the Challenges of Unraveling the Genetics of FSHD
Oct 21, 2010
University of Rochester published interview with Dr. Rabi Tawil.
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Stephen Tapscott comments on DUX4 collaboration
Sep 20, 2010
An international research collaboration that includes research groups funded by the Friends of FSH Research has made a critical advance in determining the cause of FSHD.
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Identification of DNA Region Necessary for FSHD
Sep 20, 2010
An international collaboration identifies a region of DNA necessary for FSHD and focuses attention on DUX4 as the cause of muscle deterioration.
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September 2010 FSH Research Meeting
Sep 16, 2010
This brought together the various labs which have been collaborating in an effort to push ahead on FSH research through an open exchange of unpublished research.
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Clinical Study Participants Needed-Department of Clinical Physiology of the University Hospital of Montpellier, France
Jul 25, 2010
Clinical study participants needed.